Nova Express is a 1964 novel by William S. Burroughs. It was written using the cut-up method, developed by Burroughs with Brion Gysin, of enfolding snippets of different texts into the novel. It is the third book in The Nova Trilogy, preceded by The Soft Machine and The Ticket That Exploded. Burroughs considered the trilogy a "sequel" or "mathematical" continuation of Naked Lunch.
Nova Express was nominated for the Nebula Award for Best Novel in 1965.