Noradrenergic and Specific Serotonergic Antidepressant - List of NaSSAs

List of NaSSAs

The NaSSAs include the following agents:

  • Aptazapine (CGS-7525A)
  • Esmirtazapine (ORG-50,081)
  • Mianserin (Bolvidon, Norval, Tolvon)
  • Mirtazapine (Remeron, Avanza, Zispin)
  • Setiptiline (Tecipul)

Notably, all of these compounds are analogues and are also classified as tetracyclic antidepressants (TeCAs) based on their chemical structures.

Recently, S32212, a structurally novel NaSSA with an improved selectivity profile (e.g., no antihistamine effects, etc.), has been developed. It has completed preliminary preclinical research and may go on to undergo clinical trials.

Read more about this topic:  Noradrenergic And Specific Serotonergic Antidepressant

Famous quotes containing the words list of and/or list:

    Shea—they call him Scholar Jack—
    Went down the list of the dead.
    Officers, seamen, gunners, marines,
    The crews of the gig and yawl,
    The bearded man and the lad in his teens,
    Carpenters, coal-passers—all.
    Joseph I. C. Clarke (1846–1925)

    Weigh what loss your honor may sustain
    If with too credent ear you list his songs,
    Or lose your heart, or your chaste treasure open
    To his unmastered importunity.
    William Shakespeare (1564–1616)