History
For about 100 years, the scientific community has repeatedly changed its collective mind over what viruses are. First seen as poisons, then as life-forms, then biological chemicals, and today many scientists think of viruses as existing at the border between chemistry and life: a gray area between living and nonliving.
The issue of life without cellular structure came again to the fore with the 2003 discovery that the large and complex Mimivirus can synthesize proteins. This discovery suggests the possibility that some viruses may have evolved from earlier forms that could produce proteins independent of a host cell. If so, there may at one time have been a viral domain of life. It is not clear that all small viruses have originated from more complex viruses by means of genome size reduction. A viral domain of life may only be relevant to certain large viruses such as nucleocytoplasmic large DNA viruses like the Mimivirus. A 2012 study suggests that the giant viruses, such as Mimivirus, are a separate domain of life, alongside the traditional three of eukarya, prokarya and archaea, by studying the protein folding structure made by the viruses. The study concluded that giant viruses have evolved from more complex organisms into their highly parasitic form, and are an ancient lineage, alongside that of the other domains.
Viral self-assembly has implications for the study of the origin of life, as it lends further credence to the hypothesis that life could have started as self-assembling organic molecules.
Read more about this topic: Non-cellular Life
Famous quotes containing the word history:
“The history of all hitherto existing society is the history of class struggles.”
—Karl Marx (1818–1883)
“The history of all countries shows that the working class exclusively by its own effort is able to develop only trade-union consciousness.”
—Vladimir Ilyich Lenin (1870–1924)
“Spain is an overflow of sombreness ... a strong and threatening tide of history meets you at the frontier.”
—Wyndham Lewis (1882–1957)