Nob may refer to:
- Nob, Israel, a place in the vicinity of Jerusalem
- Nederlandse Onderwatersport Bond, the Dutch Underwater Federation, member of the CMAS
- Non-occluded baculovirus, a genus of virus
- Newell's Old Boys, Argentinian football team
- NoB, Japanese singer Nobuo Yamada
- Nob Yoshigahara, a Japanese puzzle-maker
- Narodnoosvobodilna borba, World War II Yugoslavian resistance
- Nob Hill, San Francisco, a neighborhood in the California city
- "one for his nob", a score in cribbage
- a person of social standing (cf. nobility)
- Derogatory term for a man's penis, typically used as an insult in the UK and Ireland.