Nile Blue in Oncology
Derivatives of Nile blue are potential photosensitizers in photodynamic therapy of malignant tumors. These dyes aggregate in the tumor cells, especially in the lipid membranes, and/or are sequestered and concentrated in subcellular organelles.
With the Nile blue derivative N-Ethyl-Nile Blue (EtNBA), normal and premalignant tissues in animal experiments can be distinguished by fluorescence spectroscopy in fluorescence imaging. EtNBA shows no phototoxic effects.
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Famous quotes containing the words nile and/or blue:
“Hard by the lilied Nile I saw
A duskish river dragon stretched along.
The brown habergeon of his limbs enamelled
With sanguine alamandines and rainy pearl:
And on his back there lay a young one sleeping,
No bigger than a mouse;”
—Thomas Lovell Beddoes (1803–1849)
“Tommy is three and when he’s bad
his mother dances with him.
She puts on the record,
“Red Roses for a Blue Lady”
and throws him across the room.”
—Anne Sexton (1928–1974)