Niculescu, a family name common in Romania, may refer to:
- Bogdan Niculescu-Duvăz, politician and architect
- Cezar Niculescu, basketball player
- Claudiu Niculescu, soccer player
- Dan Niculescu, basketball player
- Monica Niculescu, tennis player
- Radu Niculescu, soccer player
- Stefan Niculescu, composer