NF may refer to:
- Science and medical
- Neurofibromatosis, a medical disorder in which nerve tissues grow tumors
- Necrotizing fasciitis, a disease commonly known as flesh-eating bacteria
- Nod factor, a kind of molecule
- Noise figure, a concept in radar signal processing
- National Formulary, a manual of medicines
- Companies and organizations
- Air Vanuatu, IATA airline designator NF
- National Front (disambiguation), the name of many political parties
- NF Board, a football association
- Nuestra Familia, a criminal organization
- Geography
- Newfoundland and Labrador, a Canadian province, former postal code NF
- Norfolk Island, part of the Commonwealth of Australia
- Other uses
- New Foundations, an axiomatic set theory in mathematical logic
- Normal forms (databases), criteria for determining a table's degree of vulnerability to logical inconsistencies and anomalies.