Major Intersections
The entire route is in Suffolk County.
| Location | Mile | km | Destinations | Notes |
|---|---|---|---|---|
| Amityville | 0.00 | 0.00 | NY 27A (Montauk Highway) | |
| 1.18 | 1.90 | NY 27 (Sunrise Highway) | Cloverleaf interchange | |
| East Farmingdale | 2.63 | 4.23 | Southern State Parkway | Exits 32N-S (Southern State Parkway) |
| 4.83 | 7.77 | NY 24 (Conklin Street) | Eastern terminus of NY 24 (western segment) | |
| Melville | 7.80 | 12.55 | I-495 (Long Island Expressway) | Exits 49N-S (I-495) |
| 8.86 | 14.26 | Northern State Parkway | Exit 40S–N (Northern State Parkway) | |
| South Huntington | 11.09 | 17.85 | NY 25 (Jericho Turnpike) | |
| Huntington | 14.49 | 23.32 | NY 25A (Main Street) | |
| Halesite | 15.84 | 25.49 | Youngs Hill Road |
Read more about this topic: New York State Route 110
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