Nevoid Basal Cell Carcinoma Syndrome - Components

Components

Some or all of the following may be seen in someone with Gorlin Syndrome:

  1. Multiple basal cell carcinomas of the skin
  2. Odontogenic keratocyst: Seen in 75% of patients and is the most common finding. There are usually multiple lesions found in the mandible. They occur at a young age (19 yrs average).
  3. Rib and vertebrae anomalies
  4. Intracranial calcification
  5. Skeletal abnormalities: bifid ribs, kyphoscoliosis, early calcification of falx cerebri (diagnosed with AP radiograph)
  6. Distinct faces: frontal and temporopariental bossing, hypertelorism, and mandibular prognathism

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    Hence, a generative grammar must be a system of rules that can iterate to generate an indefinitely large number of structures. This system of rules can be analyzed into the three major components of a generative grammar: the syntactic, phonological, and semantic components.
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