Neuroligin - Genetics

Genetics

Neuroligins have been identified in both vertebrates and invertebrates, including humans, rodents, chickens, Drosophila melanogaster, Caenorhabditis elegans, honeybees, and Aplysia. Three genes for neuroligin expression have been found in mice and rats, while humans express five genes. Drosophila express four genes, honeybees express five genes, and both C. elegans and Aplysia express a single gene for neuroligin.

The known neuroligin genes in "Homo Sapiens" include NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN5 (also known as NLGN4Y). Each gene has been found to have unique influences on synaptic transmission.

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