Neuraminidase - Subtypes

Subtypes

Swiss-Prot lists 137 types of neuraminidase from various species as of October 18, 2006 (2006 -10-18). Nine subtypes of influenza neuraminidase are known; many occur only in various species of duck and chicken. Subtypes N1 and N2 have been positively linked to epidemics in man, and strains with N3 or N7 subtypes have been identified in a number of isolated deaths.

The following is a list of major classes of neuraminidase enzymes:

  • Viral neuraminidase
  • Bacterial neuraminidase
  • Mammalian neuraminidases:
sialidase 1 (lysosomal sialidase)
Identifiers
Symbol NEU1
Entrez 4758
HUGO 7758
OMIM 608272
RefSeq NM_000434
UniProt Q99519
Other data
Locus Chr. 6 p21
sialidase 2 (cytosolic sialidase)
Identifiers
Symbol NEU2
Entrez 4759
HUGO 7759
OMIM 605528
RefSeq NM_005383
UniProt Q9Y3R4
Other data
Locus Chr. 2 q37
sialidase 3 (membrane sialidase)
Identifiers
Symbol NEU3
Entrez 10825
HUGO 7760
OMIM 604617
RefSeq NM_006656
UniProt Q9UQ49
Other data
Locus Chr. 11 q13.5
sialidase 4
Identifiers
Symbol NEU4
Entrez 129807
HUGO 21328
OMIM 608527
RefSeq NM_080741
UniProt Q8WWR8
Other data
Locus Chr. 2 q37.3

Read more about this topic:  Neuraminidase