Scaffold Topography
The most basic characteristic of a nerve guidance conduit is its three-dimensional structure, or scaffold topography. Scaffold topography can affect various growth parameters of the implanted cells such as cell adhesion, morphology, viability, apoptosis, genetic regulation, and motility. In tissue engineering, the three main levels of scaffold structure are considered to be:
- the superstructure, the overall shape of the scaffold;
- the microstructure, the cellular level structure of the surface; and
- the nanostructure, the subcellular level structure of the surface.
Read more about this topic: Nerve Guidance Conduit
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