Nature Versus Nurture - Advanced Techniques

Advanced Techniques

The power of quantitative studies of heritable traits has been expanded by the development of new techniques. Developmental genetic analysis examines the effects of genes over the course of a human lifespan. For example, early studies of intelligence, which mostly examined young children, found that heritability measures 40–50%. Subsequent developmental genetic analyses found that variance attributable to additive environmental effects is less apparent in older individuals, with estimated heritability of IQ being higher than that in adulthood.

Another advanced technique, multivariate genetic analysis, examines the genetic contribution to several traits that vary together. For example, multivariate genetic analysis has demonstrated that the genetic determinants of all specific cognitive abilities (e.g., memory, spatial reasoning, processing speed) overlap greatly, such that the genes associated with any specific cognitive ability will affect all others. Similarly, multivariate genetic analysis has found that genes that affect scholastic achievement completely overlap with the genes that affect cognitive ability.

Extremes analysis, examines the link between normal and pathological traits. For example, it is hypothesized that a given behavioral disorder may represent an extreme of a continuous distribution of a normal behavior and hence an extreme of a continuous distribution of genetic and environmental variation. Depression, phobias, and reading disabilities have been examined in this context.

For a few highly heritable traits, some studies have identified loci associated with variance in that trait in some individuals. For example, research groups have identified loci that are associated with schizophrenia (Harrison and Owen, 2003) in subsets of patients with that diagnosis.

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