Natalia may refer to:
- Natalia (given name), list of people with this name
- Natalia (Belgian singer), birth name Natalia Druyts
- Places
- Natalia Republic, a former republic in South Africa
- Natalia, Greater Poland Voivodeship (west-central Poland)
- Natalia, Masovian Voivodeship (east-central Poland)
- Natalia, Texas, a city in Medina County, Texas, United States
- Music and film
- Natalia (film), a 1988 French film
- "Natalia", a 1981 song by Van Morrison
- "Natalia", a Venezuelan Waltz by Antonio Lauro
- Ships
- USS Natalia (SP-1251), a United States Navy patrol boat in commission from 1917 to 1918