Na+/K+-ATPase - Function

Function

The Na+/K+-ATPase helps maintain resting potential, avail transport, and regulate cellular volume. It also functions as signal transducer/integrator to regulate MAPK pathway, ROS, as well as intracellular calcium. In most animal cells, the Na+/K+-ATPase is responsible for about 1/5 of the cell's energy expenditure. For neurons, the Na+/K+-ATPase can be responsible for up to 2/3 of the cell's energy expenditure.

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