The word Muskingum derives from a similarly sounding Delaware (Native American) word, which some claim to translate as 'Eye of the Elk.'
Muskingum may refer to:
- Muskingum College
- Muskingum County, Ohio
- Muskingum County Speedway
- Muskingum River
- Muskingum Township, Ohio (disambiguation) (2 different townships)