Indications
Muromonab-CD3 is approved for the therapy of acute, glucocorticoid resistant rejection of allogeneic renal, heart and liver transplants. Unlike the monoclonal antibodies basiliximab and daclizumab, it is not approved for prophylaxis of transplant rejection, although a 1996 review has found it to be safe for that purpose.
It has also been investigated for use in treating T-cell acute lymphoblastic leukemia.
Read more about this topic: Muromonab-CD3
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