Multiple Displacement Amplification - Advantages

Advantages

MDA generates sufficient yield of DNA products. It is a powerful tool of amplifying DNA molecules from samples, such as uncultured microorganism or single cells to the amount that would be sufficient for sequencing studies. The large size of MDA-amplified DNA products also provides desirable sample quality for identifying the size of polymorphic repeat alleles. Its high fidelity also makes it reliable to be used in the single-nucleotide polymorphism (SNP) allele detection. Due to its strand displacement during amplification, the amplified DNA has sufficient coverage of the source DNA molecules, which provides high quality product for genomic analysis. The products of displaced strands can be subsequently cloned into vectors to construct library for subsequent sequencing reactions.

Read more about this topic:  Multiple Displacement Amplification

Famous quotes containing the word advantages:

    For, the advantages which fashion values, are plants which thrive in very confined localities, in a few streets, namely. Out of this precinct, they go for nothing; are of no use in the farm, in the forest, in the market, in war, in the nuptial society, in the literary or scientific circle, at sea, in friendship, in the heaven of thought or virtue.
    Ralph Waldo Emerson (1803–1882)

    ... is it not clear that to give to such women as desire it and can devote themselves to literary and scientific pursuits all the advantages enjoyed by men of the same class will lessen essentially the number of thoughtless, idle, vain and frivolous women and thus secure the [sic] society the services of those who now hang as dead weight?
    Sarah M. Grimke (1792–1873)

    The advantages found in history seem to be of three kinds, as it amuses the fancy, as it improves the understanding, and as it strengthens virtue.
    David Hume (1711–1776)