MTC may stand for:
- Magnetic Torquer Coil, an interface used in satellite to control its finer movements
- Management and Training Corporation, a contractor known for its private prisons
- Mandarin Training Center at National Taiwan Normal University
- Manhattan Theatre Club, a non-profit theatre company located in New York, NY
- Manitoba Theatre Centre, a regional theatre located in Winnipeg, Manitoba
- MAPSA Technology Center, a technology center located in Tehran, Iran
- Maritime Trading Center, a television station in Constanţa, Romania
- Mars Coordinated Time, the form of timekeeping on Mars
- Mass Transportation Centre
- McLaren Technology Centre, headquarters of the McLaren Group
- Mechanised Transport Corps, a British women's organisation in World War II
- Medullary thyroid cancer
- Meet the Composer, an American organization that seeks to assist composers
- Melbourne Theatre Company
- Metropolitan Transition Center, a prison
- Metropolitan Transit Commission, the transit authority in Minneapolis-Saint Paul now known as Metro Transit
- Metropolitan Transport Corporation (Chennai)
- Metropolitan Transportation Commission (San Francisco Bay Area)
- Micropinnacle Technology Corporation, an Information Technology Corporation in the Philippines
- MIDI timecode
- Minimum Toxic Concentration/Maximum Tolerated Concentration, Pharmacokinetic terms, both with the same meaning
- Ministry of Transport and Communications (Venezuela)
- Missionary Training Center, for The Church of Jesus Christ of Latter-day Saints
- Mississippi Teacher Corps
- Mobile Telecommunications Company, a telecommunications company in Kuwait
- Mobile Telecommunications Limited, a Namibian cellular network
- Mobile Terminated Call
- Mongolia Telecom Company
- Montreal Toral Center, a Chabad-Lubavitch synagogue in Montreal
- Montreal Transit Corporation
- Mormon Tabernacle Choir, sponsored by The Church of Jesus Christ of Latter-day Saints
- Morgan Technical Ceramics
- Move The Crowd Records Ltd., a record company in New Zealand.
- Multiple testing correction or multiple test correction in statistical hypothesis testing
- Mitsubishi Training Center in Okazaki, Japan
- United Nations Convention on International Multimodal Transport of Goods (Geneva, 24 May 1980)
- Multistate Tax Commission