MSH3

MSH3

Identifiers Symbols MSH3; DUP; MRP1 External IDs OMIM: 600887 MGI: 109519 HomoloGene: 1829 GeneCards: MSH3 Gene

Gene Ontology
Molecular function	• Y-form DNA binding • loop DNA binding • double-strand/single-strand DNA junction binding • single-stranded DNA binding • protein binding • ATP binding • DNA-dependent ATPase activity • centromeric DNA binding • enzyme binding • mismatched DNA binding • guanine/thymine mispair binding • dinucleotide insertion or deletion binding • single guanine insertion binding • dinucleotide repeat insertion binding • oxidized purine DNA binding • protein homodimerization activity
Cellular component	• nuclear chromosome • nucleus • MutSbeta complex
Biological process	• meiotic mismatch repair • DNA repair • mismatch repair • reciprocal meiotic recombination • somatic recombination of immunoglobulin gene segments • maintenance of DNA repeat elements • negative regulation of DNA recombination • positive regulation of helicase activity
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 4437 17686 Ensembl ENSG00000113318 ENSMUSG00000014850 UniProt P20585 P13705 RefSeq (mRNA) NM_002439 NM_010829 RefSeq (protein) NP_002430 NP_034959 Location (UCSC) Chr 5:
79.95 – 80.17 Mb Chr 13:
92.21 – 92.36 Mb PubMed search

DNA mismatch repair protein Msh3 is a protein that in humans is encoded by the MSH3 gene.