MPG or mpg may refer to:
- .mpg, one of a number of file extensions for MPEG-1 or MPEG-2 audio and video compression
- General Motors Milford Proving Ground
- Havas Media, formerly known as Media Planning Group, a media division of Havas
- M.P.G., an album by Marvin Gaye
- Manual pulse generator, a device normally associated with numerically controlled machinery
- Mark-Paul Gosselaar (born 1974), an American actor
- Max Planck Society (Max-Planck-Gesellschaft), a German non-profit research organization
- Miles per gallon, a motor fuel consumption measurement
- Minutes Per Game in basketball
- Motor Press Guild, a non-profit association for professionals within the motoring press
- Multiplayer game
- Multi-Touch, Physics and Gestures, a type of computer touch screen
- The Music Producers Guild (UK)