Anatomy and Physiology
| Branch of NS | Position | Neurotransmitter |
|---|---|---|
| Somatic | n/a | Acetylcholine |
| Parasympathetic | Preganglionic | Acetylcholine |
| Parasympathetic | Ganglionic | Acetylcholine |
| Sympathetic | Preganglionic | Acetylcholine |
| Sympathetic | Ganglionic | Norepinephrine* |
Motoneuron neurotransmitters |
||
According to their targets, motor neurons are classified into three broad categories:
Somatic motor neurons, which originate in the central nervous system, project their axons to the target tissues, which are always skeletal muscles. Skeletal muscles are involved in locomotion (such as the muscles of the limbs, abdominal, and intercostal muscles).
Special visceral motor neurons, also called branchial motor neurons, which directly innervate branchial muscles (that motorize the gills in fish and the face and neck in land vertebrates).
General visceral motor neurons (visceral motor neurons for short) which indirectly innervate cardiac muscle and smooth muscles of the viscera ( the muscles of the arteries): they synapse onto neurons located in ganglia of the autonomic nervous system (sympathetic and parasympathetic), located in the peripheral nervous system (PNS), which themselves directly innervate visceral muscles (and also some gland cells).
In other words:
- the motor command of skeletal and branchial muscles is monosynaptic (involving only one motor neuron, respectively, somatic and branchial, which synapses onto the muscle).
- the command of visceral muscles is disynaptic (involving two neurons: the general visceral motor neuron located in the CNS, which synapses onto a ganglionic neuron, located in the PNS, which synapses onto the muscle).
It could be argued that, in the command of visceral muscles, the ganglionic neuron, parasympathetic or sympathetic, is the real motor neuron, being the one that directly innervates the muscle (whereas the general visceral motor neuron is, strictly speaking, a preganglionic neuron). But, for historical reasons, the term motor neuron is reserved for the CNS neuron.
All vertebrate motor neurons are cholinergic, that is, they release the neurotransmitter acetylcholine. Parasympathetic ganglionic neurons are also cholinergic, whereas most sympathetic ganglionic neurons are noradrenergic, that is, they release the neurotransmitter noradrenaline. (see Table)
Read more about this topic: Motorneuron
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