Molluscum Contagiosum - Diagnosis

Diagnosis

Diagnosis is made on the clinical appearance; the virus cannot routinely be cultured. The diagnosis can be confirmed by excisional biopsy.

Histologically, molluscum contagiosum is characterized by molluscume bodies in the epidermis above the stratum basale, which consist of large cells with:

  • abundant granular eosinophilic cytoplasm (accumulated virons), and
  • a small peripheral nucleus.

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