Surname
- Binyam Mohamed, Ethiopian detained in Guantanamo Bay between 2004 and 2009
- Clara Muhammad, born Clara Evans, wife of Nation of Islam leader Elijah Muhammad
- Elijah Muhammad (1897–1975), born Elijah Poole, African American religious leader
- Ghulam Mohammad (disambiguation), various people
- Idris Muhammad, born Leo Morris, American musician
- Kenny Muhammad, beatboxer
- Khalid Sheikh Mohammed (1964 or 1965–), Confessed mastermind of numerous terror plots, including the September 11 attacks and others
- John Allen Muhammad, born John Allen Williams, American spree killer
- Mike Mohamed, American football player
- Muhsin Muhammad, American football player
- Ramzi Mohammed, Somalian bomber in the failed 21 July 2005 London bombings
- Ruby Muhammad, American centenarian
- Shabazz Muhammad (born 1993), American basketball player
- Patronymics
- Abu Bakr ibn Muhammad ibn Hazm (?–?), Scholar
- Fatimah bint Muhammad (disputed–632), The Prophet's daughter
- Ibrahim ibn Muhammad (?–?), The Islamic Prophet's son
- Qasim ibn Muhammad (?–605), The Islamic Prophet's son
- Zainab bint Muhammad, The Islamic Prophet's daughter
- Ruqayyah bint Muhammad, The Islamic Prophet's daughter
- Umm Kulthum bint Muhammad, The Islamic Prophet's daughter
- Mahathir Mohamad (born 1925), Malaysian politician; Prime Minister of Malaysia (1981–2003)
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