In Science and Technology
- Mark (designation), a designation used to identify versions of a product or item
- Megakelvin (MK), an SI unit of temperature
- Midkine, a protein
- Millikelvin (mK), an SI unit of temperature
- Mk reference point, an interface of the IP Multimedia Subsystem used to exchange messages between BGCFs in different networks
- mk (software), a make replacement in the Plan 9 from Bell Labs and Inferno operating systems
- MK spectral classification, a stellar classification system based on spectral lines
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