Test Method
If the problem is a simple factor deficiency, mixing the patient plasma 1:1 with plasma that contains 100% of the normal factor level results in a level ≥50% in the mixture (say the patient has an activity of 0%; the average of 100% + 0% = 50%). The PT or PTT will be normal (the mixing study shows correction). Correction with mixing indicates factor deficiency; failure to correct indicates an inhibitor.
Read more about this topic: Mixing Study
Famous quotes containing the words test and/or method:
“The final test of a novel will be our affection for it, as it is the test of our friends, and of anything else which we cannot define.”
—E.M. (Edward Morgan)
“The most passionate, consistent, extreme and implacable enemy of the Enlightenment and ... all forms of rationalism ... was Johann Georg Hamann. His influence, direct and indirect, upon the romantic revolt against universalism and scientific method ... was considerable and perhaps crucial.”
—Isaiah Berlin (b. 1909)