Junction List
| County | Location | Mile | km | Destinations | Notes |
|---|---|---|---|---|---|
| Osage |
Linn | 0.0 | 0.0 | US 50 | Western terminus |
| Chamois | 17.9 | 28.8 | Route 89 | Northern terminus of Route 89 | |
| Gasconade |
Hermann | 41.2 | 66.3 | Route 19 | Western end of Route 19 concurrency |
| 42.0 | 67.6 | Route 19 | Eastern end of Route 19 concurrency | ||
| Franklin |
62.2 | 100.1 | Route 185 – Sullivan | Northern terminus of Route 185 | |
| Washington | 70.3 | 113.1 | Route 47 – St. Clair | ||
| Gray Summit | 82.1 | 132.1 | I-44/US 50 | Diamond interchange | |
| St. Louis |
Wildwood | 95.7 | 154.0 | Route 109 (Eatherton Road) | Diamond interchange |
| Ellisville | 98.9 | 159.2 | Route 340 (Clarkson Road, Kiefer Creek Road) | Southern terminus of Route 340 | |
| Manchester | 103.1 | 165.9 | Route 141 (Woods Mill Road) | SPUI | |
| Des Peres | 106.5 | 171.4 | I-270 | Partial cloverleaf interchange | |
| Kirkwood | 108.9 | 175.3 | US 61/67 (N. Kirkwood Road) | ||
| City of St. Louis |
121.0 | 194.7 | Bridge over I-55 | Eastern terminus; no connection between I-55 and Route 100 | |
1.000 mi = 1.609 km; 1.000 km = 0.621 mi
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Read more about this topic: Missouri Route 100
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