1955
Danville and Mount Vernon folded. New teams in Kokomo, Indiana and Lafayette, Indiana formed and joined the league.
| Dubuque Packers | Chicago White Sox | 74-52 |
| Mattoon Phillies | Philadelphia Phillies | 68-57 |
| Clinton Pirates | Pittsburgh Pirates | 68-57 |
| Kokomo Giants | 64-62 | |
| Lafayette Chiefs | Cleveland Indians | 63-63 |
| Decatur Commodores | St. Louis Cardinals | 62-64 |
| Paris Lakers | Brooklyn Dodgers | 62-64 |
| Hannibal Citizens | 42-84 |
Dubuque beat Clinton 2 games to none, and Mattoon beat Kokomo 2 games to none, in the first round of the playoffs. Dubuque won the championship over Mattoon 3 games to none. The team from Hannibal folded. All other teams from the league became charter members of the new, Class D Midwest League, now a Low Class A circuit, and the Mississippi-Ohio Valley League folded.
Read more about this topic: Mississippi-Ohio Valley League