Misfit may refer to:
- "Misfit" (short story), a short story by Robert A. Heinlein
- Misfit (Marvel Comics), a fictional male supervillain
- Misfit (DC Comics), a fictional female vigilante
- Misfit (rapper), a rapper in the hip hop group Rascalz
- "Misfit" (song), a song by Amy Studt
- "Misfit" (song), a song by Elefant
- "Misfit", a song by Curiosity Killed the Cat
- The Misfit, character in Flannery O'Connor's short story A Good Man Is Hard to Find
- Misfit stream (or river), geographical term, one too small to have carved out the valley in which it flows.
- Salah Asuhan (film), a 1972 Indonesian film released internationally as The Misfit