Mir-19 Micro RNA Precursor Family

Mir-19 Micro RNA Precursor Family

There maybe 89 known sequences today in the microRNA 19 (miR-19) family but it will change quickly. They are found in a large number of vertebrate species. The miR-19 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. Within the human and mouse genome there are three copies of this microRNA that are processed from multiple predicted precursor hairpins:

  • mouse:
* miR-19a on chromosome 14 (MI0000688)
* miR-19b-1 on chromosome 14 (MI0000718)
* miR-19b-2 on chromosome X (MI0000546)
  • human:
* miR-19a on chromosome 13 (MI0000073)
* miR-19b-1 on chromosome 13 (MI0000074)
* miR-19b-2 on chromosome X (MI000075).

MiR-19 has now been predicted or experimentally confirmed (MIPF0000011). In this case the mature sequence is excised from the 3' arm of the hairpin precursor.

Read more about Mir-19 Micro RNA Precursor Family:  Origins, Expression

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