Minimaze Procedure - Mechanism of Elimination of Atrial Fibrillation

Mechanism of Elimination of Atrial Fibrillation

The mechanism by which AF is eliminated by curative procedures such as the maze, minimaze, or catheter ablation is controversial. All successful methods destroy tissue in the areas of the left atrium near the junction of the pulmonary veins, hence these regions are thought to be important. A concept gaining support is that paroxysmal AF is mediated in part by the autonomic nervous system and that the intrinsic cardiac nervous system, which is located in these regions, plays an important role. Supporting this is the finding that targeting these autonomic sites improves the likelihood of successful elimination of AF by catheter ablation.

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