Mielke may refer to:
- Benjamin Mielke (born 1981), German bobsledder
- Erich Mielke (1907 – 2000), Head of the East-German Stasi 1957-1989
- Gary Mielke (born 1963), American Baseball player
- Günter Mielke (1942 – 2010), West German long-distance runner
- Marcus Mielke (born 1975), German rower
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