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Osterholm serves on the editorial boards of five journals, and is a reviewer for another two dozen. He is a past president of the Council of State and Territorial Epidemiologists (CSTE) and has served on the CDC National Center for Infectious Diseases Board of Scientific Counselors from 1992 to 1997.
Osterholm serves on the IOM Forum on Emerging Infections. He has served on the IOM Committee on Emerging Microbial Threats to Health in the 21st Century and the IOM Committee on Food Safety, Production to Consumption, and he was a reviewer for the IOM Report on Chemical and Biological Terrorism. He is a frequent consultant to the World Health Organization (WHO), the National Institutes of Health (NIH), the Food and Drug Administration (FDA), the Department of Defense, and the CDC.
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