Metachromatic leukodystrophy (MLD, also called Arylsulfatase A deficiency) is a lysosomal storage disease which is commonly listed in the family of leukodystrophies as well as among the sphingolipidoses as it affects the metabolism of sphingolipids. Leukodystrophies affect the growth and/or development of myelin, the fatty covering which acts as an insulator around nerve fibers throughout the central and peripheral nervous systems. MLD involves sulfatide accumulation.
Read more about Metachromatic Leukodystrophy: Causes, Genetics, Incidence, Symptoms and Forms, Treatment, Research Towards Effective Therapies and Clinical Trials