Metabolic bone disease is an umbrella term referring to abnormalities of bones caused by a broad spectrum of disorders.
Most commonly these disorders are caused by abnormalities of minerals such as calcium, phosphorus, magnesium or vitamin D leading to dramatic clinical disorders that are commonly reversible once the underlying defect has been treated. These disorders are to be differentiated from a larger group of genetic bone disorders where there is a defect in a specific signaling system or cell type that causes the bone disorder. There may be overlap. For example, genetic or hereditary hypophosphatemia may cause the metabolic bone disorder osteomalacia. Although there is currently no treatment for the genetic condition, replacement of phosphate often corrects or improves the metabolic bone disorder.
Read more about Metabolic Bone Disease: Conditions Considered To Be Metabolic Bone Disorders
Famous quotes containing the words bone and/or disease:
“Fowls in the frith,
Fishes in the flood,
And I must wax wod:
Much sorrow I walk with
For best of bone and blood.”
—Unknown. Fowls in the Frith. . .
Oxford Book of Short Poems, The. P. J. Kavanagh and James Michie, eds. Oxford University Press.
“Health is a state of complete physical, mental and social well-being, and not merely the absence of disease or infirmity.”
—Constitution of the World Health Organization.