Messer may refer to:
- Messer (weapon), class of single-edged bladed weapon
- Messer, Oklahoma, United States
People with the given name Messer:
- David ben Judah Messer Leon (c. 1470 – 1526), Italian rabbi, physician and writer
- Judah Messer Leon (1166), French tosafist
- Judah Messer Leon (15th century), Italian rabbi, teacher, physician, and philosopher
People with the surname Messer:
- Casey Messer (born 1983), beauty queen
- Chris Messer (21st century), United States singer
- Dale Messer (21st century), Navy Chief Warrant Officer
- Danny Messer, television series character from CSI: NY
- David Messer (21st century), Australian cartoonist
- Don Messer (1909–1973), Canadian musician
- Donald E. Messer (born 1941), American United Methodist theologian and author
- Erica Messer (21st century), American television writer, producer and story editor
- Frank Messer (1925–2001), American sportscaster
- Glenn Edmund Messer (1895–1995), aviation pioneer
- Jonathan Messer (born 1973), Australian director
- Sam Messer (21st century), American painter
- Sarah Messer (born 1966), American poet and author
- Thomas M. Messer (born 1920), director of the Solomon R. Guggenheim Foundation 1961–1988
Messers may refer to :
- The Messers, an alternate name for the 1895 Partie de cartes film