Mesoporous Silica - Biosensors

Biosensors

The structure of these particles allows them to be filled with a fluorescent dye that would normally be unable to pass through cell walls. The MSN material is then capped off with a molecule that is compatible with the target cells. When the MSNs are added to a cell culture, they carry the dye across the cell membrane. These particles are optically transparent, so the dye can be seen through the silica walls. The dye in the particles does not have the same problem with self-quenching that a dye in solution has. The types of molecules that are grafted to the outside of the MSNs will control what kinds of biomolecules are allowed inside the particles to interact with the dye.

Read more about this topic:  Mesoporous Silica