Meningococcal Vaccination and People With Chronic Medical Conditions
Persons with component deficiencies in the final common complement pathway (C3,C5-C9) are more susceptible to N. meningitidis infection than complement-satisfactory persons, and it was estimated that the risk of infection is 7000 times higher in such individuals. In addition, complement component-deficient population frequently experience frequent meningococcal disease since their immune response to natural infection may be less complete than that of complement none-deficient persons.
Inherited properdin deficiency also is related with an increased risk of contracting meningococcal disease. Because persons with functional or anatomic asplenia may not immune to efficiently clear encapsulated Neisseria meningitidis from the bloodstream Persons with other conditions associated with immunosuppression also may be at increased risk of developing meningitis disease.
Read more about this topic: Meningococcal Disease
Famous quotes containing the words people, chronic, medical and/or conditions:
“We have so many people who can’t see a fat man standing beside a thin one without coming to the conclusion that the fat man got that way by taking advantage of the thin one!”
—Ronald Reagan (b. 1911)
“Perhaps our originality manifests itself most strikingly in what we do with that which we did not originate. To discover something wholly new can be a matter of chance, of idle tinkering, or even of the chronic dissatisfaction of the untalented.”
—Eric Hoffer (1902–1983)
“One fellow I was dating in medical school ... was a veterinarian and he wanted to get married. I said, but you’re going to be moving to Minneapolis, and he said, oh, you can quit and I’ll take care of you. I said, “Go.””
—Sylvia Beckman (b. c. 1931)
“In societies where modern conditions of production prevail, all of life presents itself as an immense accumulation of spectacles. Everything that was directly lived has moved away into a representation.”
—Guy Debord (b. 1931)