Megacolon - Treatment

Treatment

Possible treatments include:

  • In stable cases, use of laxatives and bulking agents, as well as modifications in diet and stool habits are effective.
  • Corticosteroids and other anti-inflammatory medication is used in toxic megacolon.
  • Antibiotics are used for bacterial infections such as Vancomycin for Clostridium Difficile
  • Disimpaction of feces and decompression using anorectal and nasogastric tubes.
  • When megacolon worsens and the conservative measures fail to restore transit, surgery may be necessary.

There are several surgical approaches to treat megacolon, such as a colectomy (removal of the entire colon) with ileorectal anastomosis (ligation of the remaining ileus and rectum segments), or a total proctocolectomy (removal of colon, sigmoid and rectum) followed by ileostomy or followed by ileoanal anastomosis.

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