Neuropathic Pain
Hyperalgesia and allodynia are examples of neuropathic pain. It is thought that the activation of specialized neuronal nociceptors are responsible for hyperalgesia. Studies suggest that hyperalgesia and allodynia are set off and sustained by certain groups of mechanosensitive sensory neurons. There is a general consensus among the scientific community that neuropeptides and NMDA receptors are crucial to the initiation of sensitization states such as hyperalgesia and allodynia.
Read more about this topic: Mechanosensation
Famous quotes containing the word pain:
“Yet here at least an earnest sense
Of human right and weal is shown;
A hate of tyranny intense,
And hearty in its vehemence,
As if my brother’s pain and sorrow were my own.
O Freedom! if to me belong
Nor mighty Milton’s gift divine,
Nor Marvell’s wit and graceful song.
Still with a love as deep and strong
As theirs, I lay, like them, my best gifts on thy shrine!”
—John Greenleaf Whittier (1807–1892)