Measles - Epidemiology

Epidemiology

In 2000 the WHO estimated that there were ~45 million cases of measles worldwide with 800,000 deaths from it. Mortality in developed countries is ~1/1000. In sub-Saharan Africa, mortality is 10%. In cases with complications, the rate may rise to 20–30%. In 2010, approximately 380 deaths occurred every day from measles.

Even in countries where vaccination has been introduced, rates may remain high. In Ireland, vaccination was introduced in 1985. The number of cases was 99,903 in that year. Within two years, the number of cases had fallen to 201, but this fall was not sustained: case numbers in 1989, 1993 and 2000 were 1,248, 4,328 and 1,603, respectively. This country's example illustrates the need for vaccination rates greater than 95% to prevent the spread of measles.

According to the WHO, measles is a leading cause of vaccine-preventable childhood mortality. Worldwide, the fatality rate has been significantly reduced by a vaccination campaign led by partners in the Measles Initiative: the American Red Cross, the United States Centers for Disease Control and Prevention (CDC), the United Nations Foundation, UNICEF and the WHO. Globally, measles fell 60% from an estimated 873,000 deaths in 1999 to 345,000 in 2005. Estimates for 2008 indicate deaths fell further to 164,000 globally, with 77% of the remaining measles deaths in 2008 occurring within the Southeast Asian region.

In 2006-07 there were 12,132 cases in 32 European countries: 85% occurred in five countries: Germany, Italy, Romania Switzerland and the UK. 80% occurred in children and there were 7 deaths.

Five out of six WHO regions have set goals to eliminate measles, and at the 63rd World Health Assembly in May 2010, delegates agreed a global target of a 95% reduction in measles mortality by 2015 from the level seen in 2000, as well as to move towards eventual eradication. However, no specific global target date for eradication has yet been agreed to as of May 2010.

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