As A Surname
- Alastair McIntosh (1955-), Scottish writer, academic and activist
- Andrew McIntosh (professor) (1952-), Professor of Thermodynamics at the University of Leeds and director of Truth in Science.
- Andrew McIntosh, Lord McIntosh of Haringey (1933–2010), British Labour politician
- Charles Macintosh (1766–1843), Scottish inventor
- Charles Henry Mackintosh (1820–1896), Irish preacher and Christian writer
- Charles Rennie Mackintosh (1868–1928), Scottish architect and designer
- Donald McIntosh (1838–1876), Canadian-born officer in Custer's 7th Cavalry who was killed at Little Big Horn
- Donald McIntosh (1868–1957), mathematician
- Colonel E. E. B. Mackintosh, Director of the Science Museum, London
- Ewart Alan Mackintosh (1893–1917), lieutenant in the British army during the First World War and a war poet
- Hamish McIntosh, Australian Rules footballer
- Harold Mackintosh, 1st Viscount Mackintosh of Halifax, (1891–1964), son of confectioner John Mackintosh
- James M. McIntosh, American Civil War general in the Confederate army
- John Baillie McIntosh, American Civil War general in the Union army
- John F. McIntosh (1846–1918), Scottish engineer
- John S. McIntosh, paleontologist
- John Mackintosh (1868–1920), founder of the UK confectionery company Mackintosh's
- Lachlan McIntosh, American Revolutionary War general
- Lucy Mackintosh (b. 1956), co-owner of Lucy Mackintosh Contemporary Art Gallery, Lausanne, Switzerland
- Maggie McIntosh, U.S. politician from Maryland
- Pat McIntosh, Scottish mystery writer
- Robert J. McIntosh (b. 1922), U.S. Representative from Michigan
- Sir Robert Reynolds Macintosh (1897–1989), first Nuffield Professor of Anaesthetics, Oxford
- Stephanie McIntosh (b. 1985), Australian singer
- Winston Hubert McIntosh (1944–1987), better known as Peter Tosh
- Captain John McIntosh Mohr, Father of Captain William McIntosh
- Captain William McIntosh, Father of Chief William McIntosh
- William McIntosh (1775–1825), Chief of the Lower Creek Indians
- Kelsey McIntosh (b. 1987), cat enthusiast
- William Carmichael McIntosh, 19th century scientist and winner of the Royal Medal in 1899 and the Linnean Medal in 1924
- W. S. McIntosh, civil rights leader in Dayton, Ohio in the 1960s and 1970s
- Naraine McIntosh, Christian minister, leader of the Christ Life Ministry
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