Marquardt is a surname of German origin. Notable people with the surname include:
- Bridget Marquardt (born 1973), American television personality, glamour model, and actress
- Christel Marquardt, judge on the Kansas Court of Appeals
- Christiane Marquardt (born 1958), retired East German sprinter
- Darcy Marquardt (born 1979), Canadian rower
- David Marquardt, co-founder of venture capital firm August Capital
- Donald Marquardt (1929–1997), American statistician
- Elizabeth Marquardt, author of Between Two Worlds: The Inner Lives of Children of Divorce
- Heinz Marquardt (1922–2003), German Luftwaffe fighter ace
- Joachim Marquardt (1812–1882), German historian and writer on Roman antiquities
- Markus Marquardt (born 1970), German operatic baritone
- Mike Marquardt (born 1982), American football defensive tackle
- Nate Marquardt (born 1979), American mixed martial artist
- Ollie Marquardt (1902–1968), infielder in Major League Baseball
- R. Niels Marquardt (born 1953), American diplomat
- Stephen R. Marquardt
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