Markowitz is a surname and may refer to:
- Deborah Markowitz, Vermont secretary of state
- Harry Markowitz, a financial economist and Nobel Laureate
- John Markowitz, professor of psychiatry at Weill Cornell Medical College
- Kate Markowitz, American singer-songwriter
- Marty Markowitz, Brooklyn borough president
- Michael Markowitz, Emmy-nominated writer, producer, and actor
- Mitch Markowitz, Canadian television executive
- Phil Markowitz, a pianist
- William Markowitz, American astronomer
- The Family Markowitz, 1996 novel
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