Marker Assisted Selection - Selection For Major Genes Linked To Markers

Selection For Major Genes Linked To Markers

The major genes which are responsible for economically important characteristics are frequent in the Plant Kingdom. Such characteristics include disease resistance, male sterility, self-incompatibility, others related to shape, color, and architecture of whole plants and are often of mono- or oligogenic in nature. The marker loci which are tightly linked to major genes can be used for selection and are sometimes more efficient than direct selection for the target gene. Such vantages in efficiency may be due for example, to higher expression of the marker mRNA in such cases that the marker is actually a gene. Alternatively, in such cases that the target gene of interest differs between two alleles by a difficult-to-detect single nucleotide polymorphism, an external marker (be it another gene or a polymorphism that is easier to detect, such as a short tandem repeat) may present as the most realistic opti.

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