Marker Assisted Selection - Positive and Negative Selectable Markers

Positive and Negative Selectable Markers

  • Positive selectable markers are selectable markers that confers selective advantage to its host organism. An example would be antibiotics resistance, which allows the host organism to survive antibiotics selection.
  • Negative selectable markers are selectable markers that would eliminate its host organism upon selection. An example would be thymidine kinase, which would make the host sensitive to ganciclovir selection.

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