Positive and Negative Selectable Markers
- Positive selectable markers are selectable markers that confers selective advantage to its host organism. An example would be antibiotics resistance, which allows the host organism to survive antibiotics selection.
- Negative selectable markers are selectable markers that would eliminate its host organism upon selection. An example would be thymidine kinase, which would make the host sensitive to ganciclovir selection.
Read more about this topic: Marker Assisted Selection
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