Background
Maria Sophie was the eldest child of Landgrave Charles of Hesse-Kassel and Princess Louise of Denmark, born in Hanau. Her paternal grandparents were Frederick II of Hesse-Kassel and Princess Mary of Great Britain, a daughter of King George II and Caroline of Ansbach. Her maternal grandparents were Frederick V of Denmark and Louise of Great Britain, another daughter of George II and Caroline of Ansbach. Her father was the second son of the ruler of Hesse-Kassel, and as such, had no principality of his own. Thus he acted in such positions as were offered to cadet members of royal houses by their reigning relatives. Denmark offered more and better positions than the small Hesse-Kassel.
Marie Sophie grew up largely in Denmark, where her father held notable positions, such as the governorships of provinces. Her mother was the third and youngest daughter of King Frederick V of Denmark and his consort, Louise of Great Britain. As such, she was the niece of King Christian VII and the Prince Regent Frederik, as well as their first cousin.
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