Malnutrition–inflammation complex (syndrome), abbreviated as “MICS” and also known as "malnutrition–inflammation–cachexia syndrome", is a common condition in chronic disease states such as chronic kidney disease (where it is also known as uremic malnutrition or protein–energy malnutrition) and chronic heart failure.
The MICS is believed to be a cause of survival paradoxes seen in these distinct patient populations, also known as reverse epidemiology populations.
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“All of life and human relations have become so incomprehensibly complex that, when you think about it, it becomes terrifying and your heart stands still.”
—Anton Pavlovich Chekhov (1860–1904)