Malaria - Cause

Cause

Malaria parasites are from the genus Plasmodium (phylum Apicomplexa). In humans, malaria is caused by P. falciparum, P. malariae, P. ovale, P. vivax and P. knowlesi. Among those infected, P. falciparum is the most common species identified (~75%) followed by P. vivax (~20%). P. falciparum accounts for the majority of deaths; non-falciparum species have been found to be the cause of about 14% of cases of severe malaria in some groups. P. vivax proportionally is more common outside of Africa. There have been documented human infections with several species of Plasmodium from higher apes; however, with the exception of P. knowlesi—a zoonotic species that causes malaria in macaques—these are mostly of limited public health importance.

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