Macaco can refer to:
- Macaco - a martial arts technique used in capoeira
- Macaco (band) - a musical band.
- A comics character and periodical created by K-Hito (1890-1984)
- The Portuguese variant of the pejorative epithet, Macaca (slur)
- Jorge Patino, Brazilian mixed martial arts fighter
- Macaco is the Portuguese word for Monkey.